Machine-intelligent systems and processes are no longer simply science fiction. Users are now surrounded by an overwhelming amount of digitally intelligent applications. These applications, though often undetected, are integrated seamlessly and become deeply influential in the design of digital products’ user experiences. This pervasive implementation contrasts starkly with a blank space in the critical academic discussion of applied AI-based design practices. The conference raises questions that result from designing of, with and for machine learning algorithms and assist systems: How do designers’ traditional understandings change if the machine makes fundamental and far-reaching design decisions in the blink of an eye and ceases to be a mere passive design tool. If predictions become a major part of the user experience as well as the information design? What ramifications do these changes have on the notion of creativity? Also, how can designers (re-)design human-machine participation? Lastly, how does machine learning alter strategic design, corporate identity and the idea of personal design aesthetics? To answer these questions we invite selected experts from the fields of design, science, art and industry to present keynotes. Additionally, the conference is scheduled to provide a rich program of talks, workshops, and experimental formats. Designing with Artificial Intelligence/DAI aims to bring together a diverse audience of design practitioners, design managers, design theorists and design leaders interested in the pressing questions raised.